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ARTICLE · 18 MAY 2025

Lessons From Landmark Jury Verdict In Amitiza Reverse Payment Antitrust Case

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A federal jury awarded $885 million against Takeda Pharmaceuticals for an anticompetitive patent settlement that delayed generic competition for its IBS drug Amitiza.

United StatesAntitrust/Competition Law

On May 18, a federal jury in Massachusetts returned a $885 million verdict against Takeda Pharmaceuticals, finding that Takeda entered into an anticompetitive patent settlement that compensated a generic manufacturer to delay launching a generic version of its IBS drug, Amitiza® (lubiprostone). In re Amitiza Antitrust Litigation, No. 1:21-cv-11057 (D. Mass.). The suit consolidated complaints filed by a class of direct purchasers (wholesalers), five individual retailers (pharmacy chains), and a class of indirect purchasers (end payors). The outcome is significant because it is the first jury trial win for private antitrust plaintiffs in a suit challenging a patent settlement reverse payment. Previous suits have either settled or gone to trial and lost. For Brand and Generic pharmaceutical manufacturers, this may lead to further scrutiny of past settlements.

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