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ARTICLE · 01 JULY 2025

IARC Classifies Automotive Gasoline As Carcinogenic To Humans

Bryan Cave Leighton Paisner
Bryan Cave Leighton Paisner
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Bryan Cave Leighton Paisner

Bryan Cave Leighton Paisner

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The International Agency for Research on Cancer (IARC)—a branch of the World Health Organization mandated to investigate potential causes of cancer—conducts its own hazard evaluations of suspected carcinogens...

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The International Agency for Research on Cancer (IARC)—a branch of the World Health Organization mandated to investigate potential causes of cancer—conducts its own hazard evaluations of suspected carcinogens and publishes its classifications in IARC Monographs. As IARC's own Q&A document explains, these classifications "indicate the strength of the evidence as to whether an agent is capable of causing cancer (technically called "hazard"), but it does not measure the likelihood that cancer will occur (technically called "risk") at a particular level of exposure to the agent."1

IARC's latest monograph from their February-March 2025 Working Group evaluated "automotive gasoline and some oxygenated gasoline additives."2 Based on their assessment, IARC assigned automotive gasoline to Group 1 (carcinogenic to humans) and gasoline additives to Group 2B (possibly carcinogenic to humans).3 With this Group 1 classification, gasoline joins the consumption of processed

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