ECHA Updates Recommendations To Improve REACH Registrations

On February 28, 2023, the European Chemicals Agency (ECHA) announced that it updated its recommendations to improve Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) registrations. According to ECHA, the recommendations are based on ECHA's findings from registration dossier compliance checks and take recent changes to REACH information requirements into account. The recommendations focus on the rules for using adaptations to assess the safety of chemicals without animal testing. ECHA states that they provide advice on read-across, covering considerations on structural similarity, defining substance groups, and predicting target substance properties. ECHA also provided information on adaptations based on exposure scenarios outlined in chemical safety reports. According to ECHA, further advice addresses the requirements for mutagenicity information and chronic aquatic toxicity studies for poorly soluble substances. ECHA recommends that