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ARTICLE · 27 MAY 2024

PTAB Reaffirms Written Description Threshold When Claiming A Genus

On May 17, 2024, the Patent Trial and Appeal Board (PTAB) affirmed a rejection of a claim directed to a purification method using single-domain antigen-binding proteins...

United StatesIntellectual Property

On May 17, 2024, the Patent Trial and Appeal Board (PTAB) affirmed a rejection of a claim directed to a purification method using single-domain antigen-binding proteins that bind mammalian IgG as lacking adequate written description (Appeal 2023-000567). The claim at issue in U.S. Application No. 16/282,082 (the '082 Application) recites:

Claim 77. A method for the purification of a molecule comprising an epitope present in the Fc domain of a human IgG antibody, the method comprising the steps of:

a) bringing a sample comprising the molecule comprising the epitope present in the Fc domain of a human IgG antibody into contact with an immunoadsorbent material comprising a variable heavy-heavy (VHH) antigen-binding protein under conditions that allow for binding of the molecule to the immunoadsorbent material;

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