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ARTICLE · 31 AUGUST 2026

EPA Still Has Authority To Regulate In The Face Of Uncertainty

A federal appeals court has unanimously upheld EPA's authority to designate PFOA and PFOS as hazardous substances under CERCLA, reaffirming the agency's power to regulate environmental threats even when scientific certainty is incomplete. The decision, which included one of the most prominent anti-regulatory appellate judges, reinforces a 50-year precedent that allows EPA to act on scientific probabilities rather than absolute proof when protecting public health and the environment.

United StatesEnvironment

Last week, in Chamber of Commerce v. EPA, the D.C. Circuit Court of Appeals rejected challenges to EPA’s decision to list PFOA and PFOS, the two most prominent PFAS compounds, as hazardous substances under CERCLA. It’s an important decision, and not just because pressure to clean up sites contaminated with PFAS seems to be increasing every day.

It’s also important because the opinion contains an unqualified affirmation of EPA’s authority to regulate under uncertainty. As I’ve noted previously in this space, EPA’s authority to regulate under uncertainty was originally established in Ethyl Corp. v. EPA. It has not been seriously questioned in the 50 years since Ethyl Corp. v. EPA was decided.

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