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ARTICLE · 12 DECEMBER 2018

Can Patents Help Regulate Future Experimentation With Designer Babies?

The objective was to prevent the twin baby girls from acquiring HIV infection by modifying their genes.

South AfricaIntellectual Property

Jiankui He, an associate professor of bioengineering who is currently on leave from Southern University of Science and Technology, in Shenzhen, China, has claimed to be the first to successfully bring to life two genetically-edited twin girls, Lulu and Nana. The objective was to prevent the twin baby girls from acquiring HIV infection by modifying their genes.

Jiankui He's team carried out this procedure using the CRISPR-Cas9. Named breakthrough of 2015 by Science magazine, CRISPR-Cas9 is a gene-editing tool that holds the promise of potentially fixing diseases by precisely cutting and pasting specific gene(s) among the 20,000 human genes.

In this case, by injecting CRISPR-Cas9 into a human egg and implanting the genetically-edited embryos back into the mother, Jiankui He's work specifically targets the CCR5 gene that is responsible for producing a protein that HIV uses to invade the white blood cells. Specifically, his research has knocked out this gene to render

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